Search results for "Otorhinolaryngologic Neoplasms"

showing 3 items of 3 documents

Population attributable risk of tobacco and alcohol for upper aerodigestive tract cancer.

2011

Tobacco and alcohol are major risk factors for upper aerodigestive tract (UADT) cancer and significant variation is observed in UADT cancer rates across Europe. We have estimated the proportion of UADT cancer burden explained by tobacco and alcohol and how this varies with the incidence rates across Europe, cancer sub-site, gender and age. This should help estimate the minimum residual burden of other risk factors to UADT cancer, including human papillomavirus. We analysed 1981 UADT cancer cases and 1993 controls from the ARCAGE multicentre study. We estimated the population attributable risk (PAR) of tobacco alone, alcohol alone and their joint effect. Tobacco and alcohol together explaine…

AdultMaleCancer Researchmedicine.medical_specialtyAlcohol DrinkingEsophageal NeoplasmsAlcoholchemistry.chemical_compoundRisk FactorsTobaccomedicineHumansPopulation attributable riskGynecologyMouth neoplasmbusiness.industryIncidenceMedicine (all)Incidence (epidemiology)SmokingCase-control studyCancerAlcohol; ARCAGE study; Population attributable risk; Tobacco; Upper aerodigestive tract cancer; Adult; Alcohol Drinking; Case-Control Studies; Esophageal Neoplasms; Europe; Female; Humans; Incidence; Male; Middle Aged; Mouth Neoplasms; Otorhinolaryngologic Neoplasms; Risk Factors; Smoking; Oral Surgery; Medicine (all); Oncology; Cancer ResearchMiddle Agedmedicine.diseaseUpper aerodigestive tract cancerARCAGE studyEuropeOtorhinolaryngologic NeoplasmsUpper aerodigestive tractOncologychemistryCase-Control StudiesAttributable riskFemaleMouth NeoplasmsUpper aerodigestive tract cancer; ARCAGE study; Population attributable risk; Tobacco; AlcoholOral SurgeryAlcoholbusinessOropharyngeal CancersDemography
researchProduct

Selection of optimal prophylactic aminoglycoside dosage in cancer patients: population pharmacokinetic approaches.

1994

We report an alternative dose-finding approach for the selection of optimal prophylactic aminoglycoside dosage in specific (sub)populations of patients. Relative a priori utility of several intervals of gentamicin or tobramycin (AMG) peak and trough serum levels were assigned by a group of pharmacokinetics experts, assuming prophylactic administration for laryngectomy interventions. A group of 27 adult patients, with normal renal function, undergoing elective surgery for laryngeal problems and treated prophylactically with gentamicin (80 mg t.i.d.) or tobramycin (100 mg t.i.d.) was studied. Two blood samples (peak and trough) were drawn at steady-state for AMG assay. Three different methods…

AdultMalemedicine.medical_specialtyDosePremedicationPopulationUrologyPharmacologyPharmacokineticsmedicineTobramycinHumansPharmacology (medical)educationSelection (genetic algorithm)Antibacterial agentAgedPharmacologyAged 80 and overeducation.field_of_studybusiness.industryClindamycinAminoglycosideMiddle AgedAnti-Bacterial AgentsOtorhinolaryngologic NeoplasmsTobramycinGentamicinFemaleGentamicinsbusinessmedicine.drugJournal of clinical pharmacy and therapeutics
researchProduct

Imaging of cervical lymph node metastases in malignant jugular paraganglioma: Imaging of paraganglioma metastases

2009

Not available

medicine.medical_specialtyEar MiddleparagangliomaText miningParagangliomamedicineHumansLymph nodeParaganglioma Extra-Adrenalbusiness.industryJugular paragangliomamedicine.diseaseSensory SystemsRadiographyOtorhinolaryngologic Neoplasmsmedicine.anatomical_structureCarotid ArteriesOtorhinolaryngologylymphonodeLymphatic Metastasismalignant paragangliomaNeurology (clinical)RadiologyLymph NodesJugular VeinsbusinessMagnetic Resonance AngiographyNeck
researchProduct